Copper is essential for optimal surgical outcomes due to its role in strengthening connective tissues through collagen and elastin cross-linking, which supports tissue integrity during and after surgery. It also aids in red blood cell production, promoting adequate oxygenation critical for healing. As an antioxidant, copper helps reduce oxidative stress and inflammation, supporting cellular health throughout recovery. Additionally, it contributes to energy production for cellular repair and influences neurotransmitter synthesis, which aids in stress resilience and stable circadian rhythms during recovery. Insufficient copper levels can delay wound healing and weaken tissue, making adequate copper intake crucial for surgical patients.

Mechanisms of Action and Benefits:

• Collagen and Elastin Cross-Linking: Copper supports lysyl oxidase, an enzyme that strengthens connective tissue.
• Red Blood Cell and Hemoglobin Synthesis: Essential for cardiovascular health through red blood cell formation.
• Antioxidant Protection: Supports superoxide dismutase (SOD), defending cells against free radicals and tissue damage.
• Energy Production: Aids mitochondrial function for efficient energy metabolism.
• Neurotransmitter Synthesis: Involved in creating catecholamines and melatonin, promoting brain health, and regulating circadian rhythms.

References:

1. https://traceelements.com/Docs/The%20Nutritional%20Relationships%20of%20Copper.pdf Accessed October 2024
2. Jessica Salvo, Cristian Sandoval, Role of copper nanoparticles in wound healing for chronic wounds: literature review, Burns & Trauma, Volume 10, 2022
3. Ruiz LM, Libedinsky A, Elorza AA. Role of Copper on Mitochondrial Function and Metabolism. Front Mol Biosci. 2021;8:711227. Published 2021 Aug 24. doi:10.3389/fmolb.2021.711227
4. Sirisha Karri, Vaishali Doshi; Hematological Abnormalities in Copper Deficiency.. Blood 2007; 110 (11): 2677.